Wednesday, 4 September 2013

Methamphetamine Recreational Use: Effects.

Physical:

Physical effects can include anorexia, hyperactivity, dilated pupils, flushed skin, excessive sweating, restlessness, dry mouth and bruxism (leading to "meth mouth"), headache, accelerated heartbeat, slowed heartbeat, irregular heartbeat, rapid breathing, high blood pressure, low blood pressure, high body temperature, diarrhea, constipation, blurred vision, dizziness, twitching, insomnia, numbness, palpitations, tremors, dry and/or itchy skin, acne, pallor, and – with chronic and/or high doses – convulsions,heart attack, stroke & death.

Psychological:

Psychological effects can include euphoria, anxiety, increased libido, alertness, concentration, increased energy, increased self-esteem, self-confidence, sociability, irritability, aggressiveness, psychosomatic disorders, psychomotor agitation, dermatillomania (compulsive skin picking), hair pulling, delusions of grandiosity, hallucinations, excessive feelings of power and invincibility, repetitive and obsessive behaviors, paranoia, and – with chronic use and/or high doses – amphetamine psychosis.

Withdrawal:

Withdrawal symptoms of methamphetamine primarily consist of fatigue, depression, and increased appetite. Symptoms may last for days with occasional use and weeks or months with chronic use, with severity dependent on the length of time and the amount of methamphetamine used. Withdrawal symptoms may also include anxiety, irritability, headaches, agitation, restlessness, excessive sleeping, vivid or lucid dreams, deep REM sleep, and suicidal ideation.

Long-term:

Methamphetamine use has a high association with depression and suicide as well as serious heart disease, amphetamine psychosis, anxiety, and violent behaviors. Methamphetamine also has a very high addiction risk. Unlike cocaine and amphetamine, methamphetamine is directly neurotoxic to midbrain dopamine neurons. Moreover, methamphetamine use is associated with an increased risk of Parkinson's disease due to the fact that uncontrolled dopamine effluxion is neurotoxic. Long-term dopamine upregulation occurring as a result of methamphetamine abuse can also cause neurotoxicity, which is believed to be responsible for causing persisting cognitive deficits, such as memory loss, impaired attention, and decreased executive function. Similar to the neurotoxic effects on the dopamine system, methamphetamine can also result in neurotoxicity to serotonergic neurons.
As a result of methamphetamine-induced neurotoxicity to dopaminergic neurons, chronic use may also lead to post acute withdrawals which persist beyond the withdrawal period for months, and even up to a year. A study performed on female Japanese prison inmates suffering from methamphetamine addiction showed that 49% experienced "flashbacks" afterward and 21% experienced a psychosis resembling schizophrenia which persisted for longer than six months post-methamphetamine use; this amphetamine psychosis could be resistant to traditional treatment. Other studies in Japan show that those who experience methamphetamine-induced psychosis are much more likely to experience psychotic symptoms again if they use methamphetamine. In addition to psychological harm, physical harm – primarily consisting of cardiovascular damage – may occur with chronic use or acute overdose.

Tolerance:

As with other amphetamines, tolerance to methamphetamine is not completely understood but is known to be sufficiently complex that it cannot be explained by any single mechanism. The extent of tolerance and the rate at which it develops vary widely between individuals, and even within one person. It is highly dependent on dosage, duration of use, and frequency of administration. Tolerance to the awakening effect of amphetamines does not readily develop, making them suitable for the treatment of narcolepsy. Short-term tolerance can be caused by depleted levels of neurotransmitters within the synaptic vesicles available for release into the synaptic cleft following subsequent reuse (tachyphylaxis). Short-term tolerance typically lasts until neurotransmitter levels are fully replenished; because of the toxic effects on dopaminergic neurons, this can be greater than 2–3 days. Prolonged overstimulation of dopamine receptors caused by methamphetamine may eventually cause the receptors to downregulate in order to compensate for increased levels of dopamine within the synaptic cleft. To compensate, larger quantities of the drug are needed in order to achieve the same level of effects. Reverse tolerance or sensitization can also occur. The effect is well established, but the mechanism is not well understood.
 

Methamphetamines; Make, Use, From & Look:


The chemical n-methyl-1-phenyl-propan-2-amine is called methamphetamine, methyl-amphetamine, or desoxyephedrine. The shortened name is simply 'meth'. When it is in its crystalline form, the drug is called crystal meth, ice, Tina, or glass. See the table below for other street names of the drug. Methamphetamine is a highly addictive stimulant.  

Use and Effects of Crystal Meth

Crystal meth is snorted, injected, or smoked in a pipe. It is taken to produce feelings of euphoria or a“ high” that can last between two and 16 hours. People abuse crystal meth, which is a central nervous system stimulant, to stay awake for long periods or make them feel confident, energized, euphoric and disinhibited.
 
Crystal meth use has many adverse effects on the mind and body. Most common are:
  • insomnia
  • agitation
  • irritability
  • dry mouth
  • sweating
  • palpitations

On crystal meth, the body temperature increases, as does breathing and heart rate. Blood pressure rises too. People with cardiac and blood pressure problems who use crystal meth can cause further damage to their cardiovascular systems.
Crystal meth can cause behavioral problems, paranoia and psychosis, especially when used frequently and in individuals with a predisposition to mental illness.
 
 What Does Crystal METH Look like?
 
Crystal meth usually comes in the form of a crystalline clear or white powder that is odorless, bitter-tasting and dissolves easily in water or alcohol. The clear crystals may appear with some other shades of colour such as yellow / champagne colour or dark yellow.


Drug Strength:

Users of crystal meth can only guess at its strength, so the risk of overdosing, even with seemingly small quantities, is always an issue. Overdosing can lead to convulsions, respiratory and circulatory collapse, coma and death.
 
Where Does Crystal Meth Come From?

Methamphetamine is available with a prescription for obesity, attention deficit hyperactivity disorder, and narcolepsy, but crystal meth is a street drug, made in illegal labs by chemically altering over-the-counter drugs. Making crystal meth usually involves reducing ephedrine or pseudoephedrine, found in cold and allergy medicine. In the US, a typical meth lab employs something called the 'Red, White, and Blue Process', which entails hydrogenation of the hydroxyl group on the ephedrine or pseudoephedrine molecule. The red is red phosphorus, white is the ephedrine or pseudoephedrine, and blue is iodine, used to make hydroiodic acid. Making crystal meth is dangerous to the people making it and dangerous to the neighborhood where it's being made. White phosphorus with sodium hydroxide can produce poisonous phosphine gas, usually as a result of overheating red phosphorus, plus white phosphorus can autoignite and blow up the meth lab. In addition to phosphine and phosphorus, various hazardous vapors may be associated with a meth lab, such as chloroform, ether, acetone, ammonia, hydrochloric acid, methylamine, iodine, hydroiodic acid, lithium or sodium, mercury & hydrogen gas.
 
 
 

 

My name is?!

I destroy homes, I tear families apart,
take your children, and that's just the start.
I'm more costly than diamonds, more precious than gold,
The sorrow I bring is a sight to behold.

If you need me, remember I'm easily found,
I live all around you - in schools and in towns
I live with the rich; I live with the poor,
I live down the street, and maybe next door.

I'm made in a lab, but not like you think,
I can be made under the kitchen sink.
In your child's closet, and even in the woods,
If this scares you to death, well it certainly should.

I have many names, but there's one you know best,
I'm sure you've heard of me, my name is crystal meth.
My power is awesome; try me you'll see,
But if you do, you may never break free.

Just try me once and I might let you go,
But try me twice, and I'll own your soul.
When I possess you, you'll steal and you'll lie,
You do what you have to -- just to get high.

The crimes you'll commit for my narcotic charms
Will be worth the pleasure you'll feel in your arms, your lungs your nose.
You'll lie to your mother; you'll steal from your dad,
When you see their tears, you should feel sad.

But you'll forget your morals and how you were raised,
I'll be your conscience, I'll teach you my ways.
I take kids from parents, and parents from kids,
I turn people from God, and separate friends.

I'll take everything from you, your looks and your pride,
I'll be with you always -- right by your side.
You'll give up everything - your family, your home,
Your friends, your money, then you'll be alone.

I'll take and take, till you have nothing more to give,
When I'm finished with you, you'll be lucky to live.
If you try me be warned - this is no game,
If given the chance, I'll drive you insane.

I'll ravish your body, I'll control your mind,
I'll own you completely, your soul will be mine.
The nightmares I'll give you while lying in bed,
The voices you'll hear, from inside your head.

The sweats, the shakes, the visions you'll see,
I want you to know, these are all gifts from me.
But then it's too late, and you'll know in your heart,
That you are mine, and we shall not part.

You'll regret that you tried me, they always do,
But you came to me, not I to you.
You knew this would happen, many times you were told,
But you challenged my power, and chose to be bold.

You could have said no, and just walked away,
If you could live that day over, now what would you say?
I'll be your master, you will be my slave,
I'll even go with you, when you go to your grave.

Now that you have met me, what will you do?
Will you try me or not?  It's all up to you.
I can bring you more misery than words can tell,
Come take my hand, let me lead you to hell.